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Asetil Salisilik Asit (Salisilat)

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Asetil Salisilik Asit (Salisilat)

Klinik kullanımı :

En çok kullanılan formu ASPİRİN dir. Analjezik, anti-enflamatuar ve

antipiretik olarak kullanılır. Tedavi dozunun ayarlanması ve toksik

durumun saptanması ve takibi amacıyla kullanılır.

Referans değerler

Analjezik konsantrasyon : 2-10 mg/dL, 20-100 μg/mL

Antienflamatuar konsantrasyon : 15-30 mg/dL, 150-300 μg/mL

Toksik konsantrasyon : >30 mg/dL, >300 μg/mL

#Analjezik#anti-enflamatuar#antipiretik#Aspirin

Kaynaklar ve Referanslar

  1. [1]Vane JR, Botting RM. “The mechanism of action of aspirin.”. Thrombosis research. 2003. PMID: 14592543. PubMed →
  2. [2]Kumbhani DJ, Gibson CM, Kinlay S, Peterson ED, Pollak AW, Tamis-Holland JE, Verheugt FWA. “Antiplatelet Therapy in the Management of Atherosclerotic Cardiovascular Disease: 2026 ACC Scientific Statement: A Report of the American College of Cardiology.”. Journal of the American College of Cardiology. 2026. PMID: 42377293. PubMed →
  3. [3]Pomponi M, Pomponi MF. “Alzheimer's disease prevention & acetyl salicylic acid: a believable story.”. The Indian journal of medical research. 2014. PMID: 24604034. PubMed →
  4. [4]S K, L G, S PP, C K. “Aspirin as a neuroprotective scaffold in Alzheimer's disease: inflammation, oxidative stress, and future directions.”. Molecular Biology Reports. 2026. PMID: 42118381. PubMed →
  5. [5]Krishnamoorthy K, Sherman LS, Romagano MP, et al. “Low dose acetyl salicylic acid (LDA) mediates epigenetic changes in preeclampsia placental mesenchymal stem cells similar to cells from healthy pregnancy.”. Placenta. 2023. PMID: 37071955. PubMed →
  6. [6]Lobkovich A, Ferrari H, Martirosov AL, Mohammad I, Berlie H, Garwood C, Lipari M. “Aspirin Deprescribing Interventions for Primary Prevention: A Systematic Review and Proposed Guidance for Deprescribing.”. Pharmacotherapy. 2026. PMID: 41709404. PubMed →
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