Lamotrigine (Lamictal®)
Sanal Hastane||1 dk okuma

Klinik kullanımı :
Antiepileptik bir ilaçtır. Aynı zamanda Lennox-Gustaut sendromlu
hastalarında etkilidir.
Örnek toplama özellikleri
Hastanın son ilaç kullanma zamanı ve dozu belirtilmelidir.
Referans değerler
Tedavi Dozu: 0.5-4.0 μg/mL
Toksik Doz : >8.0 μg/mL
Kaynaklar ve Referanslar
- [1]Bowden CL, Singh V. “Lamotrigine (Lamictal IR) for the treatment of bipolar disorder.”. Expert opinion on pharmacotherapy. 2012. PMID: 23140205. PubMed →
- [2]Falcicchio G, Nucera B, Giuliano L, Castellucci G, Colonna I, Russo E. “Pregnancy and epilepsy: pharmacokinetic insights into antiseizure medications”. Expert Opinion on Drug Metabolism & Toxicology. 2026. PMID: 41863508. PubMed →
- [3]Alyahya B, Friesen M, Nauche B, et al. “Acute lamotrigine overdose: a systematic review of published adult and pediatric cases.”. Clinical toxicology (Philadelphia, Pa.). 2018. PMID: 28862044. PubMed →
- [4]Mohammadi B, Mehvari J, Naghibi N, Tabrizi N. “The intersection of epilepsy and assisted reproduction: A review of therapeutic approaches and considerations”. Seizure. 2025. PMID: 41197258. PubMed →
- [5]Haenen N, Kamperman AM, Prodan A, et al. “The efficacy of lamotrigine in bipolar disorder: A systematic review and meta-analysis.”. Bipolar disorders. 2024. PMID: 38750644. PubMed →
- [6]Sang H, Zhao L, Zhang Y, Wang X, Zhang X. “Case report: late adverse reactions in an epilepsy patient on combination therapy with valproate and lamotrigine”. Acta Epileptologica. 2025. PMID: 40307904. PubMed →


