Lizozim (Muramidaz)
Sanal Hastane||1 dk okuma
Klinik kullanımı :
Başlıca granülosit ve monositlerin yıkımında oluşur. Akut veya
kronik granülositik veya monositik lösemiler, Myeloproliferatif
hastalıklar ve malign histiositozis tanısında kullanılır. Lizozim
seviyesi > 200 μg/ml plazma seviyeleri akut nonlenfositik lösemi
(M2, M4, M5) veya kronik granülositik lösemilerde görülmektedir.
Referans değerler
0.2- 15.8 μg/ml
Yükseldiği durumlar
-Akut monositik veya myelomonositik lösemi,
-Kronik myeloid lösemi,
-Polistemia vera,
-Bazı böbrek hastalıkları ve kronik enfeksiyonlarda (ör.tüberküloz)
serum lizozim düzeyi artar.
#Akut monositik lösemi#kronik enfeksiyon#Kronik myeloid lösemi#malign histiositozis#myelomonositik lösemi#Myeloproliferatif hastalıklar#Polistemia vera#Tüberküloz
Kaynaklar ve Referanslar
- [1]Qin L, Yu G, Zhou J. “Coarse-grained simulations of lysozyme-silica-nanoparticle corona.”. Biointerphases. 2023. PMID: 37195015. PubMed →
- [2]Nagase H. “A study on the clinical significance of serum and urinary muramidase activity in leukemics.”. Nagoya Journal of Medical Science. 1971. PMID: 5286505. PubMed →
- [3]Lee L, Cavalieri F, Ashokkumar M. “Exploring New Applications of Lysozyme-Shelled Microbubbles.”. Langmuir : the ACS journal of surfaces and colloids. 2019. PMID: 31088060. PubMed →
- [4]Wiernik PH, Serpick AA. “Clinical significance of serum and urinary muramidase activity in leukemia and other hematologic malignancies.”. The American Journal of Medicine. 1969. PMID: 4888852. PubMed →
- [5]Yang T, Yan W. “Strategies for enhancing the antibacterial efficacy of lysozyme and the resulting outcome.”. International journal of biological macromolecules. 2025. PMID: 40233915. PubMed →
- [6]Aström M, Bodin L, Hörnsten P, Wahlin A, Tidefelt U. “Evidence for a bimodal relation between serum lysozyme and prognosis in 232 patients with acute myeloid leukaemia.”. European Journal of Haematology. 2003. PMID: 12631256. PubMed →
