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Aldosteron (İdrar)

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Aldosteron (İdrar)

Klinik kullanımı :

İdrarda aldosteron ölçümü primer ve sekonder aldosteronizm

durumlarının araştırılması amacıyla kullanılır. İdrar aldosteron

düzeyi, üriner sodyum atılımı ile ters korelasyon gösterir.

Örnek toplama özellikleri :

Koruyucu eklenmemiş temiz bir kaba 24 saatlik idrar toplanmalıdır.

Diüretikler, siklik progestajenler, östrojenler, antihipertansif ilaçlar

ve licorice testlen 2-4 hafta önce kesilmiş olmalıdır. 24 saat

boyunca örnekler buz içinde veya buzdolabında saklanabilir.

Referans değerler :

2-26 mcg/24 saat veya 6-72 nmol/24 saat (SI unit)

#primer aldosteronizm#sekonder aldosteronizm

Kaynaklar ve Referanslar

  1. [1]Brown JM, Siddiqui M, Calhoun DA, et al. “The Unrecognized Prevalence of Primary Aldosteronism: A Cross-sectional Study.”. Annals of internal medicine. 2020. PMID: 32449886. PubMed →
  2. [2]Brown JM, Siddiqui M, Calhoun DA, et al. “The Unrecognized Prevalence of Primary Aldosteronism: A Cross-sectional Study.”. Annals of internal medicine. 2020. PMID: 32449886. PubMed →
  3. [3]Wijbenga-van der Kooi I, van Faassen M, Kerstens M, Kema IP, Vos MJ. “Urinary aldosterone and tetrahydroaldosterone by LC-MS/MS with enzymatic hydrolysis: validation and age-stratified reference intervals”. Clinical Chemistry and Laboratory Medicine. 2026. PMID: 41764747. PubMed →
  4. [4]Hung CS (å•Ÿç››) 628401, Chang YY, Tsai CH, et al. “Aldosterone suppresses cardiac mitochondria.”. Translational research : the journal of laboratory and clinical medicine. 2022. PMID: 34411778. PubMed →
  5. [5]Hung CS (å•Ÿç››) 628401, Chang YY, Tsai CH, et al. “Aldosterone suppresses cardiac mitochondria.”. Translational research : the journal of laboratory and clinical medicine. 2022. PMID: 34411778. PubMed →
  6. [6]Cheng JYK, Lo CWS, Chan ASL, Luk YK, Tsui TKC, Ho CS. “Simultaneous quantitation of urine aldosterone and tetrahydroaldosterone in healthy Chinese subjects using a validated LC-MS/MS method”. Biomedical Chromatography. 2023. PMID: 37354001. PubMed →
  7. [7]Prete A, Lang K, Pavlov D, et al. “Urine steroid metabolomics as a diagnostic tool in primary aldosteronism.”. The Journal of steroid biochemistry and molecular biology. 2024. PMID: 38104729. PubMed →
  8. [8]Prete A, Lang K, Pavlov D, et al. “Urine steroid metabolomics as a diagnostic tool in primary aldosteronism.”. The Journal of steroid biochemistry and molecular biology. 2024. PMID: 38104729. PubMed →
  9. [9]Libianto R, Uniacke CL, Fuller PJ, Young MJ, Yang J. “Beyond aldosterone and renin: emerging biomarkers for diagnosing and subtyping primary aldosteronism”. Endocrine Reviews. 2026. PMID: 42186715. PubMed →
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