İmmünfiksasyon Elektroforezi (İmmünglobulin Elektroforezi)
Sanal Hastane||1 dk okuma
Klinik kullanımı :
Multiple myeloma ve Waldenström makroglobulinemisi gibi
immünproliferatif hastalıklar ve immün yetmezliklerin tanı ve
takibinde kullanılır. Antikoagülanlar, antikonvülzanlar, oral
kontraseptifler, isoniazid ve prokainamid kullanımı tüm
immünglobulin düzeylerinde yanlış yükselmelere neden olurken,
fenitoin ve metilprednizolon kullanımı ise IgG ve IgA düzeylerinde
düşmeye neden olabilir.
Kaynaklar ve Referanslar
- [1]Willis MD, Kreft KL, Dancey B. “Oligoclonal bands.”. Practical neurology. 2024. PMID: 38937092. PubMed →
- [2]Zoungrana D, Kechaich O, Kherouf H, Chanteperdrix-Marillier V, Bourgerette-Acri E. “Multiple myeloma with atypical gammopathy: a rare case report.”. Ann Biol Clin (Paris). 2026. PMID: 42104949. PubMed →
- [3]Moore AR, Harris RA, Jeffries C, et al. “Diagnostic performance of routine electrophoresis and immunofixation for the detection of immunoglobulin paraproteins (M-Proteins) in dogs with multiple myeloma and related disorders: Part 2-Toward improved diagnostic performance.”. Veterinary clinical pathology. 2021. PMID: 33855710. PubMed →
- [4]Soliman D, Alqatati F, Mudawi D, et al.. “The Rare Trio: Concomitant Bone Marrow Involvement by Smoldering Myeloma and Systemic Mastocytosis with an Associated Hematologic Neoplasm and ALECT-2 Renal Amyloidosis - A Case Report and Literature Review.”. Case Rep Oncol. 2026. PMID: 42368884. PubMed →
- [5]Kawano Y, Nishimura N, Yasunaga JI. “Serum monoclonal immunoglobulin light-chain detection differs between immunofixation electrophoresis methods in patients with AL amyloidosis.”. International journal of hematology. 2024. PMID: 38739302. PubMed →
- [6]Sternbach N, Bishara S, Gertz MA, Vaxman I. “Waldenström Macroglobulinemia Presenting With Hepatic Lesions: Case Report and Literature Review.”. Case Rep Hematol. 2026. PMID: 42282257. PubMed →
