Tahlil

Zerit (Stavudin) (d4T)

Sanal Hastane||1 dk okuma
Zerit (Stavudin) (d4T)

Klinik kullanımı

d4T olarak bilinir. HIV enfeksiyonunun tedavisinde kullanılan etkili anti retroviral bir ilaçtır. d4T, timin analogu reverse transkriptaz inhibitörüdür.

Reklam

Referans değerler

Pik konsantrasyonu (doz alımından 1-1,5 saat sonra) :0,7-2,0 μg/ml

İlk yarı ömür konsantrasyonu (3-4 saat sonra) : 0,3-0,8 μg/ml

İdame dozu : 0,02

 

#AIDS#AIDS tedavisi#HIV enfeksiyonu

Kaynaklar ve Referanslar

  1. [1]Friedland G, Dunkle LW, Cross AP. “Stavudine (d4T, Zerit).”. Advances in experimental medicine and biology. 1996. PMID: 8815691. PubMed →
  2. [2]Podlekareva D, Grint D, Karpov I, et al.. “Changing utilization of Stavudine (d4T) in HIV-positive people in 2006-2013 in the EuroSIDA study”. HIV Medicine. 2015. PMID: 25988795. PubMed →
  3. [3]“Zerit vs. Retrovir.”. Positively aware : the monthly journal of the Test Positive Aware Network. 2000. PMID: 11366345. PubMed →
  4. [4]Spaulding A, Rutherford GW, Siegfried N. “Stavudine or zidovudine in three-drug combination therapy for initial treatment of HIV infection in antiretroviral-naive individuals”. Cochrane Database of Systematic Reviews. 2010. PMID: 20687097. PubMed →
  5. [5]Riddler SA, Anderson RE, Mellors JW. “Antiretroviral activity of stavudine (2',3'-didehydro-3'-deoxythymidine, D4T).”. Antiviral research. 1995. PMID: 8540743. PubMed →
  6. [6]Siegfried NL, Van Deventer PJU, Mahomed FA, Rutherford GW. “Stavudine, lamivudine and nevirapine combination therapy for treatment of HIV infection and AIDS in adults”. Cochrane Database of Systematic Reviews. 2006. PMID: 16625606. PubMed →
Paylaş:
← Tüm Makaleler